Diabetic Nephropathy is a complication of DMIP which is caused by Diabetes. Renal function can by reversed by proper treatment in the early stage of Diabetic Nephropathy. If Diabetic Nephropathy develop into Renal Failure or Uremia, this treatment will spend more time, money, and worst of all, the disease can't be cured. Therefore, it is very important to choose a proper treatment in the early stage of Diabetic Nephropathy.
1. Glomerular filtration stage: it is featured by increasing glomerular filtration rate and enlarging the size of kidney. These changes accompany with high blood sugar. With the help of insulin treatment, the disease can be reversed in this stage, but can't recover completely.Firstly, we need to understand the stages of Diabetic Nephropathy. That is because different stage has different treatment.
2. Kidney damage stage without any symptoms: this stage is featured by normal proteinuria discharge rate and changed glomerular structure.
3. The early stage of Diabetic Nephropathy: the discharge rate of albumin is 20--200μg/ min, patients present a slightly increased blood pressure and glomerulus begin to necrosis.
4. This stage is featured by a lot of albuminuria(>3.5g everyday),edema and high blood pressure. Diuretic medicines have little effect for patient's edema in this stage.
5. The late/end stage of renal failure: because glomerular basement membrane become more and more thick, blood capillary become more and more narrow, more and more glomeruli begin to necrosis/ sclerosis. In the end, the filtration function decrease gradually, which leads to Renal Failure.
Different period should choose different treatment.
Normally, the best treatment for the front three periods is Micro-Chinese Medicine Osmotherapy. The main therapeutic principle for Micro-Chinese Medicine is to promote blood circulation by removing blood stasis, repair the damaged cells. Clinical practice has proved that urine protein can be reduced by Micro-Chinese Medicine; meanwhile, renal function can be protected by Micro-Chinese Medicine in the early period of Diabetic Nephropathy. Furthermore, the hyperplasia of glomerular extracellular matrix can be alleviated and hardeningratio of glomerulus can be reduced.
The main function of Micro-Chinese Medicine is to promote blood circulation, remove the stasis in channels. The main pathological change of Diabetic Nephropathy is glomerulosclerosis and basement membrane damage. After superfinely shattered, the active substance can aim at expand all arteries and increase the effective blood perfusion, increase the oxygen supply of damaged glomerulus, thus improving the micro-blood circulation, promoting metabolism, alleviating and restoring the sclerosis states of glomerulus.
The best treatment for patients who in the later stage of Diabetic Nephropathy is dialysis+ Stem Cells Transplant.
In the later stage of Diabetic Nephropathy, kidney transplant can be utilized for patients, but it is not easy for general family to afford the high cost of kidney transplant. The best therapeutic method is to utilize stem cells for repairing the damaged renal cells when dialysis is maintaining the life, then stem cells can generate new nephrons to replace the dead/ anile cells, thus rebuilding the renal function, prolonging the time interval of dialysis, even let patients get rid of dialysis.
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